Article-Journal

Off by a beat: the effects of temporal misalignment in reinforcement learning for sepsis treatment

npj Digital Medicine, May 2026

Shengpu Tang, Jiayu Yao, Jenna Wiens, Sonali Parbhoo

Clinical trials for continuously monitored and updated AI systems

Nature Medicine, April 2026

Wouter A. C. Van Amsterdam, Michael Oberst, Jean Feng, Jenna Wiens, Shengpu Tang, Shalmali Joshi, Rajesh Ranganath, Mark Sendak, Uri Shalit, Julia E. Vogt, Brett Beaulieu-Jones, Muhammad Mamdani, David Kent, Patrick J. Heagerty, Thomas R. Fleming, Anna Goldenberg

Optimizing loop diuretic treatment for mortality reduction in patients with acute dyspnea using a practical offline reinforcement learning pipeline for healthcare: a retrospective single center simulation study

JMIR Medical Informatics, Sep 2025

Jung Min Lee, Shengpu Tang, Michael W. Sjoding, Jenna Wiens

Guiding Clostridioides difficile Infection Prevention Efforts in a Hospital Setting With AI

JAMA Network Open, Jun 2025

Shengpu Tang, Stephanie Shepard, Rebekah Clark, Erkin Ötleş, Chidimma Udegbunam, Josh Tran, Melinda Seiler, Justin Ortwine, Akbar K. Waljee, Jerod Nagel, Sarah L. Krein, Jacob E. Kurlander, Paul J. Grant, Jihoon Baang, Anastasia Wasylyshyn, Krishna Rao, Jenna Wiens

Early Identification of Patients Admitted to Hospital for COVID-19 at Risk of Clinical Deterioration: Model Development and Multisite External Validation Study

The BMJ (British Medical Journal), Feb 2022

Shengpu Tang^*, Fahad Kamran^*, Erkin Ötleş, Dustin S. McEvoy, Sameh N. Saleh, Jen Gong, Benjamin Y. Li, Sayon Dutta, Xinran Liu, Richard J. Medford, Thomas S. Valley, Lauren R. West, Karandeep Singh, Seth Blumberg, John P. Donnelly, Erica S. Shenoy, John Z. Ayanian, Brahmajee K. Nallamothu, Michael W. Sjoding^†, Jenna Wiens^†

Predicting Acute Graft-versus-Host Disease Using Machine Learning and Longitudinal Vital Sign Data from Electronic Health Records

JCO Clinical Cancer Informatics, 2020

Shengpu Tang, Grant T. Chappell, Amanda Mazzoli, Muneesh Tewari, Sung Won Choi^*, Jenna Wiens^*

Off by a beat: the effects of temporal misalignment in reinforcement learning for sepsis treatment

Clinical trials for continuously monitored and updated AI systems

Optimizing loop diuretic treatment for mortality reduction in patients with acute dyspnea using a practical offline reinforcement learning pipeline for healthcare: a retrospective single center simulation study

Guiding Clostridioides difficile Infection Prevention Efforts in a Hospital Setting With AI

Early Identification of Patients Admitted to Hospital for COVID-19 at Risk of Clinical Deterioration: Model Development and Multisite External Validation Study

Respecting Autonomy and Enabling Diversity: The Effect of Eligibility and Enrollment on Research Data Demographics

Predicting Postoperative Opioid Use with Machine Learning and Insurance Claims in Opioid-Naïve Patients

Democratizing EHR Analyses with FIDDLE - A Flexible Data-Driven Preprocessing Pipeline for Structured Clinical Data

Evaluating a Widely Implemented Proprietary Deterioration Index Model Among Hospitalized COVID-19 Patients

Predicting Acute Graft-versus-Host Disease Using Machine Learning and Longitudinal Vital Sign Data from Electronic Health Records